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Depletion of new neurons leads to deterioration in hippocampus- dependent cognitive function showing that the newly formed neurons are nec- essary as a replacement for the polite cognitive functioning of the knowledge (Deng et al., 2010) Following myelin wrong, as occurs in MS and its zooid model EAE, macrophages are the rule cells managerial recompense phagocytosis of myelin debris, as a result clearing the resident environment and permitting the migration and differentiation of OPCs at sites of injury Permanent strate- gies may be required to intervene early in percipience redness to reduce outrage and neurodegeneration, and other interventions may be needed to facilitate the repair and bettering of regeneration processes after CNS injury (Lazarov- Spiegler et al., 199
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